A00-B99 C00-D48D50-D89 E00-E90 F00-F99 G00-G99 H00-H59 H60-H95 I00-I99 J00-J99 K00-K93
L00-L99 M00-M99 N00-N99 O00-O99 P00-P96 Q00-Q99 R00-R99 S00-T98 V01-Y98 Z00-Z99 U00-U99

E20-E35 Disorders of other endocrine glands

Chapter IV

Endocrine, nutritional and metabolic diseases

Disorders of other endocrine glands

* galactorrhoea (N64.3)
* gynaecomastia (N62)

Latin: Hypoparathyreoidismus
Excludes:Di George's syndrome (D82.1)
postprocedural hypoparathyroidism (E89.2)
tetany NOS (R29.0)
transitory neonatal hypoparathyroidism (P71.4)
E20.0Idiopathic hypoparathyroidism
E20.8Other hypoparathyroidism
E20.9Hypoparathyroidism, unspecified
Parathyroid tetany

E21Hyperparathyroidism and other disorders of parathyroid gland
Latin: Hiperparathyreoidismus et disordines glandulae parathyreoideae alii
· adult (M83.-)
· infantile and juvenile (E55.0)
E21.0Primary hyperparathyroidism
Hyperplasia of parathyroid
Osteitis fibrosa cystica generalisata [von Recklinghausen's disease of bone]
E21.1Secondary hyperparathyroidism, not elsewhere classified
Excludes:secondary hyperparathyroidism of renal origin (N25.8)
E21.2Other hyperparathyroidism
Excludes:familial hypocalciuric hypercalcaemia (E83.5)
E21.3Hyperparathyroidism, unspecified
E21.4Other specified disorders of parathyroid gland
E21.5Disorder of parathyroid gland, unspecified

E22Hyperfunction of pituitary gland
Latin: Hyperfunctio glandulae pituitariae
Excludes:Cushing's syndrome (E24.-)
Nelson's syndrome (E24.1)
overproduction of:
· ACTH not associated with Cushing's disease (E27.0)
· pituitary ACTH (E24.0)
· thyroid-stimulating hormone (E05.8)
E22.0Acromegaly and pituitary gigantism
Arthropathy associated with acromegaly+ (M14.5*)
Overproduction of growth hormone
· gigantism (E34.4)
· tall stature (E34.4)
increased secretion from endocrine pancreas of growth hormone-releasing hormone (E16.8)
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E22.2Syndrome of inappropriate secretion of antidiuretic hormone
E22.8Other hyperfunction of pituitary gland
Central precocious puberty
E22.9Hyperfunction of pituitary gland, unspecified

E23Hypofunction and other disorders of pituitary gland
Latin: Hypopituitarismus et morbi hypophysis alii
Includes:the listed conditions whether the disorder is in the pituitary or the hypothalamus
Excludes:postprocedural hypopituitarism (E89.3)
Fertile eunuch syndrome
Hypogonadotropic hypogonadism
Idiopathic growth hormone deficiency
Isolated deficiency of:
· gonadotropin
· growth hormone
· pituitary hormone
Kallmann's syndrome
Lorain-Levi short stature
Necrosis of pituitary gland (postpartum)
· cachexia
· insufficiency NOS
· short stature
Sheehan's syndrome
Simmonds' disease
E23.1Drug-induced hypopituitarism
Use additional external cause code (Chapter XX), if desired, to identify drug.
E23.2Diabetes insipidus
Excludes:nephrogenic diabetes insipidus (N25.1)
E23.3Hypothalamic dysfunction, not elsewhere classified
Excludes:Prader-Willi syndrome (Q87.1)
Russell-Silver syndrome (Q87.1)
E23.6Other disorders of pituitary gland
Abscess of pituitary
Adiposogenital dystrophy
E23.7Disorder of pituitary gland, unspecified

E24Cushing's syndrome
Latin: Sindroma Cushing
E24.0Pituitary-dependent Cushing's disease
Overproduction of pituitary ACTH
Pituitary-dependent hyperadrenocorticism
E24.1Nelson's syndrome
E24.2Drug-induced Cushing's syndrome
Use additional external cause code (Chapter XX), if desired, to identify drug.
E24.3Ectopic ACTH syndrome
E24.4Alcohol-induced pseudo-Cushing's syndrome
E24.8Other Cushing's syndrome
E24.9Cushing's syndrome, unspecified

E25Adrenogenital disorders
Latin: Disordines adrenogenitales
Includes:adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
· adrenal pseudohermaphroditism
· heterosexual precocious pseudopuberty
· isosexual precocious pseudopuberty
· macrogenitosomia praecox
· sexual precocity with adrenal hyperplasia
virilization (female)
E25.0Congenital adrenogenital disorders associated with enzyme deficiency
Congenital adrenal hyperplasia
21-Hydroxylase deficiency
Salt-losing congenital adrenal hyperplasia
E25.8Other adrenogenital disorders
Idiopathic adrenogenital disorder
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E25.9Adrenogenital disorder, unspecified
Adrenogenital syndrome NOS

Latin: Hyperaldosteronismus
E26.0Primary hyperaldosteronism
Conn's syndrome
Primary aldosteronism due to adrenal hyperplasia (bilateral)
E26.1Secondary hyperaldosteronism
E26.8Other hyperaldosteronism
Bartter's syndrome
E26.9Hyperaldosteronism, unspecified

E27Other disorders of adrenal gland
Latin: Disordines glandulae adrenalis alli
E27.0Other adrenocortical overactivity
Overproduction of ACTH, not associated with Cushing's disease
Premature adrenarche
Excludes:Cushing's syndrome (E24.-)
E27.1Primary adrenocortical insufficiency
Addison's disease
Autoimmune adrenalitis
Excludes:amyloidosis (E85.-)
tuberculous Addison's disease (A18.7)
Waterhouse-Friderichsen syndrome (A39.1)
E27.2Addisonian crisis
Adrenal crisis
Adrenocortical crisis
E27.3Drug-induced adrenocortical insufficiency
Use additional external cause code (Chapter XX), if desired, to identify drug.
E27.4Other and unspecified adrenocortical insufficiency
· haemorrhage
· infarction
Adrenocortical insufficiency NOS
Excludes:adrenoleukodystrophy [Addison-Schilder] (E71.3)
Waterhouse-Friderichsen syndrome (A39.1)
E27.5Adrenomedullary hyperfunction
Adrenomedullary hyperplasia
Catecholamine hypersecretion
E27.8Other specified disorders of adrenal gland
Abnormality of cortisol-binding globulin
E27.9Disorder of adrenal gland, unspecified

E28Ovarian dysfunction
Latin: Dysfunctiones ovariales
Excludes:isolated gonadotropin deficiency (E23.0)
postprocedural ovarian failure (E89.4)
E28.0Estrogen excess
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E28.1Androgen excess
Hypersecretion of ovarian androgens
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E28.2Polycystic ovarian syndrome
Sclerocystic ovary syndrome
Stein-Leventhal syndrome
E28.3Primary ovarian failure
Decreased estrogen
Premature menopause NOS
Resistant ovary syndrome
Excludes:menopausal and female climacteric states (N95.1)
pure gonadal dysgenesis (Q99.1)
Turner's syndrome (Q96.-)
E28.8Other ovarian dysfunction
Ovarian hyperfunction NOS
E28.9Ovarian dysfunction, unspecified

E29Testicular dysfunction
Latin: Dysfunctiones testiculares
Excludes:androgen resistance syndrome (E34.5)
azoospermia or oligospermia NOS (N46)
isolated gonadotropin deficiency (E23.0)
Klinefelter's syndrome (Q98.0-Q98.2, Q98.4)
postprocedural testicular hypofunction (E89.5)
testicular feminization (syndrome) (E34.5)
E29.0Testicular hyperfunction
Hypersecretion of testicular hormones
E29.1Testicular hypofunction
5-Alpha-reductase deficiency (with male pseudohermaphroditism)
Defective biosynthesis of testicular androgen NOS
Testicular hypogonadism NOS
Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.
E29.8Other testicular dysfunction
E29.9Testicular dysfunction, unspecified

E30Disorders of puberty, not elsewhere classified
Latin: Disordines pubertatis
E30.0Delayed puberty
Constitutional delay of puberty
Delayed sexual development
E30.1Precocious puberty
Precocious menstruation
Excludes:Albright(-McCune)(-Sternberg) syndrome (Q78.1)
central precocious puberty (E22.8)
congenital adrenal hyperplasia (E25.0)
female heterosexual precocious pseudopuberty (E25.-)
male isosexual precocious pseudopuberty (E25.-)
E30.8Other disorders of puberty
Premature thelarche
E30.9Disorder of puberty, unspecified

E31Polyglandular dysfunction
Latin: Dysfunctiones polyglandulares endocrinae
Excludes:ataxia telangiectasia [Louis-Bar] (G11.3)
dystrophia myotonica [Steinert] (G71.1)
pseudohypoparathyroidism (E20.1)
E31.0Autoimmune polyglandular failure
Schmidt's syndrome
E31.1Polyglandular hyperfunction
Excludes:multiple endocrine adenomatosis (D44.8)
E31.8Other polyglandular dysfunction
E31.9Polyglandular dysfunction, unspecified

E32Diseases of thymus
Latin: Morbi thymi
Excludes:aplasia or hypoplasia with immunodeficiency (D82.1)
myasthenia gravis (G70.0)
E32.0Persistent hyperplasia of thymus
Hypertrophy of thymus
E32.1Abscess of thymus
E32.8Other diseases of thymus
E32.9Disease of thymus, unspecified

E34Other endocrine disorders
Latin: Disordines systematis endocrini alii
Excludes:pseudohypoparathyroidism (E20.1)
E34.0Carcinoid syndrome
Note:May be used as an additional code, if desired, to identify functional activity associated with a carcinoid tumour.
E34.1Other hypersecretion of intestinal hormones
E34.2Ectopic hormone secretion, not elsewhere classified
E34.3Short stature, not elsewhere classified
Short stature:
· constitutional
· Laron-type
· psychosocial
Excludes:progeria (E34.8)
Russell-Silver syndrome (Q87.1)
short-limbed stature with immunodeficiency (D82.2)
short stature:
· achondroplastic (Q77.4)
· hypochondroplastic (Q77.4)
· in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index
· nutritional (E45)
· pituitary (E23.0)
· renal (N25.0)
E34.4Constitutional tall stature
Constitutional gigantism
E34.5Androgen resistance syndrome
Male pseudohermaphroditism with androgen resistance
Peripheral hormonal receptor disorder
Reifenstein's syndrome
Testicular feminization (syndrome)
E34.8Other specified endocrine disorders
Pineal gland dysfunction
E34.9Endocrine disorder, unspecified
· endocrine NOS
· hormone NOS

E35*Disorders of endocrine glands in diseases classified elsewhere
Latin: Morbi glandularum endocrinarum in morbis aliis
E35.0*Disorders of thyroid gland in diseases classified elsewhere
Tuberculosis of thyroid gland (A18.8+)
E35.1*Disorders of adrenal glands in diseases classified elsewhere
Tuberculous Addison's disease (A18.7+)
Waterhouse-Friderichsen syndrome (meningococcal) (A39.1+)
E35.8*Disorders of other endocrine glands in diseases classified elsewhere